It makes a HUGE difference. I remember doing art in the dining room and yes I could manage it, BUT having a room to store supplies, hang works in progress and sit and work on projects changes the dynamics.
Routine informs the mind and having a routine in the studio is very helpful in kickstarting creative ideas and play. One of my art teachers said he used to just spend 30 minutes sweeping the floor (he had a large studio). He said it was meditative and prepared him for a day of painting, like he had conditioned himself.
I start with a cup of tea, doing a bit work on the computer, looking at my walls,